How can I get Plenity? KERI SEWELL, MD, MPH, AND AFI M. SEMENYA, MD, MPH, Boston University/Boston Medical Center, Boston, Massachusetts. Plenity has been shown in a clinical study to have a proven safety profile and is as well tolerated as a placebo (a capsule with inactive ingredients).*. Pricing shown online or via the Inside Rx app are subject to change in real time. Cheat meals and cheat days might feel like a well-earned reward, but they may be doing more harm than good when youre trying to make sustainable lifestyle changes. 2023 Jan 5;7:e40062. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. Plenity is not recommended for use during pregnancy. It works by inducing a feeling of fullness so that patients eat less and lose weight. Data sources: Watch the video below to learn more. Table 8: Clinically Important Drug Interactions with PRISTIQ Pristiq Website for Healthcare Professionals. Abstracts and posters were identified from relevant scientific congress archives and published supplements. Labeling may change as new information is learned about medications, so it's important to review the information frequently. Note: Multiple pictures are displayed for those medicines available in different strengths, marketed under different brand names and for medicines manufactured by different pharmaceutical companies. Gelesis Granted FDA Clearance to Market Plenity - a New Prescription Aid in Weight Management. If not, and you have an HSA (Health Savings Account), FSA (Flexible Spending Account), or MSA (Medical Savings Account), you should be able to use that to cover some or all of your out-of-pocket costs for Plenity. Rx Only. These rates are similar to those reported with a placebo. Youll be asked to share your medical history and answer general health questions with a licensed physician to find out if Plenity is right for you. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. For the safe and proper use of Plenity or more information, talk to a healthcare professional, read the Patient Instructions for Use, or call 1-844-PLENITY. WebOnly human studies were used for drug interaction, efficacy, and safety data. In order to provide you with relevant and meaningful content we need to know more about you. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The most common side effects were diarrhea, distended abdomen, infrequent bowel movements, and flatulence. Bethesda, MD 20894, Web Policies For a full list of Inside Rx program terms see full terms or call 800-722-8979. Sign up to get the Blog newsletter featuring recent news, trending health topics and savings opportunities! Data synthesis: Would you like to proceed? OSH offers a nonsystemic approach to weight management for patients who are diagnosed with overweight or obesity. Save 15% when you purchase a 12-week supply ($249/$1.48 per meal). This information might be about you, your preferences or your device. Plenity is a prescription-only weight loss aid. This third-party website is neither owned nor controlled by Pfizer, and Pfizer does not endorse and is not responsible for the content or services of this site. Data synthesis: OSH is a first-in-class, nonsystemic agent for weight management. Their average weight loss was 10% (about 22 pounds). Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. Reduce the dose of these drugs by up to one-half if co-administered with 400 mg of PRISTIQ. doi: 10.1002/14651858.CD008650.pub2. Plenity may affect how well your body absorbs other medications. In comparison, phentermine costs about $15 per month, and generic topiramate costs $20 per month. Call your doctor for medical advice about side effects. False-positive urine immunoassay screening tests for phencyclidine (PCP) and amphetamine have been reported in patients taking desvenlafaxine. As an alternative option to current pharmacological AOTs, OSH may address an existing clinical gap in weight management. + Company: Gelesis You can either ask your healthcare provider about Plenity, or visit MyPlenity.com to start a telehealth experience with a licensed physician. Take these 20 minutes to plan your meal and focus on you. Please change your WebThere are several risks in using Plenity, some of which might depend on other health conditions you might have. Things to remember when you fill your prescription. Contact a doctor right away if problems occur. If you miss a pre-meal dose, take Plenity with 16 oz. Sign in to view your previously saved lists. For these reasons, Plenity is considered a medical device rather than a drug, leading to a different threshold for approval. You do not need to meet with a physician in person to get Plenity! Contact a doctor right away if problems occur. antihemophilic factor (factor VIII, human)/von Willebrand factor antihemophilic factor (factor VIII, recombinant). Submit a medical question for Pfizer prescription products. They generally lessen over time and with proper use of the drug. You must drink 16 ounces of water for Plenity to work. There is limited clinical trial experience with desvenlafaxine succinate overdosage in humans. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Plenity may interfere with medication absorption and should not be taken at the same time as other medications. Greenway FL, Aronne LJ, Raben A, Astrup A, Apovian CM, Hill JO, Kaplan LM, Fujioka K, Matejkova E, Svacina S, Luzi L, Gnessi L, Navas-Carretero S, Alfredo Martinez J, Still CD, Sannino A, Saponaro C, Demitri C, Urban LE, Leider H, Chiquette E, Ron ES, Zohar Y, Heshmati HM. Bookshelf Plenity is taken as three capsules with 16 ounces (2 glasses) of water 20 minutes before lunch and dinner. Jurgens TM, Whelan AM, Killian L, Doucette S, Kirk S, Foy E. Cochrane Database Syst Rev. For current full prescribing information, please visit www.pfizer.com. ( 1) Please e-prescribe Plenity to GoGoMeds Pharmacy in Southgate, KY, or fax to (877) 766-0185. Drug interactions can also contribute to the cost of healthcare, as a serious drug interaction could result in injury, hospitalization, or rarely, death. Other side effects Other upper respiratory infections Joint pain Source: Prescribing Information Shaikh H, Bradhurst P, Ma LX, Tan SYC, Egger SJ, Vardy JL. Once prescribed, Plenity will be shipped to your home via free 2-day delivery. Careers. Usually, your doctor and pharmacist will have already done this with your prescription medications, but it's a good idea to double check and learn about these medications yourself. Tell your doctor all medications and supplements you use. If serotonin syndrome occurs, consider discontinuation of PRISTIQ and/or concomitant serotonergic drugs, other SNRIs, SSRIs, triptans, tricyclic antidepressants, fentanyl, lithium, tramadol, buspirone, amphetamines, tryptophan, and St. John's Wort. Learn more about price differences between brand and generic drugs. STEPS new drug reviews cover Safety, Tolerability, Effectiveness, Price, and Simplicity. 50 mg Tablet: light pink, square pyramid tablet debossed with "W" over "50" on the flat side Hypersensitivity to desvenlafaxine succinate, venlafaxine hydrochloride or to any excipients in the PRISTIQ formulation. False positive test results may be expected for several days following discontinuation of desvenlafaxine therapy. Share this list with your doctor, pharmacist, and nurse at each visit so that they can also screen for drug interactions. $98/4-week supply. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. HHS Vulnerability Disclosure, Help However, as a medical device, Plenity has not been held to the same standard of testing as would be expected with medications. of water during or immediately after your meal. US-PLEN-2000613 If you use any over-the-counter (OTC) medicine, including vitamins, herbal or food supplements, be sure to review these products for interactions with your prescription medications, too. Prescriptionrequired. Plenity is NOT available at retail pharmacies. The product information provided by this site is intended only for health care professionals, patients, consumers and caregivers in the United States. Most drug interactions listed in package labeling may be theoretical based on a drug's pharmacology. Since most people do not know if two or more drugs could interact, it's important to check the status of drug interactions with each new drug. Do not stop your medication without talking to your healthcare provider first. Can I use my HSA/FSA/MSA to pay for Plenity? This page cannot be displayed because your browser has been configured to The recommended dose for PRISTIQ is 50 mg once daily, with or without food. Weve made it easy to see if you qualify! Generic name: cellulose and citric acid PMC Monitor for symptoms of serotonin syndrome when PRISTIQ is used concomitantly with other drugs that may affect the serotonergic neurotransmitter systems. WebDrug-drug interactions can decrease how well your medications work, may increase minor or serious unexpected side effects, or even increase the blood level and possible toxicity The structures and properties of our superabsorbent hydrogel, Plenity, are very different from fiber. Author disclosure: No relevant financial relationships. WebWhat does Plenity look like? Please e-prescribe Plenity to GoGoMeds Pharmacy in Southgate, KY, or fax to (877) 766-0185. Only human studies were used for drug interaction, efficacy, and safety data. Because its mechanism of action is mechanical, Plenity is considered a medical device rather than a drug. Relevance to patient care and clinical practice: It has been studied in a single published trial of 436 patients with an average BMI of 34 kg per m2 who were randomized to receive treatment or placebo in addition to calorie restriction. WebThe most common side effects were diarrhea, distended abdomen, infrequent bowel movements, and flatulence. As you continue to use it, you feel fuller throughout the day. oral superabsorbent hydrogel; preobesity; weight management. Because Plenity should not be used without food (it is meant to be taken 2030 minutes before a meal), this Most drug interactions are not serious, but because a few are, it is important to understand the possible outcome before you take your medications. If you have a severe allergic reaction, severe stomach pain, or severe diarrhea, stop using Plenity until you can speak to your doctor. The result can be muscle pain, or even severe muscle injury known as rhabdomyolysis. Original dose should be taken when co-administered with PRISTIQ 100 mg or lower. 2023 Inside Rx, LLC. The most If you miss a pre-meal dose, take Plenity with 16 oz. WebThere are 6 disease interactions with Wegovy (semaglutide) which include: suicidal behavior and ideation thyroid cancer GI adverse events hypoglycemia pancreatitis retinopathy Report options Share by QR Code More about Wegovy (semaglutide) Wegovy consumer information Check interactions Pricing & coupons Reviews (129) Side effects The most common side effects were fullness, bloating, flatulence, and/or abdominal pain. Ask your pharmacist or doctor for advice if you are confused by the medical jargon. of water during or immediately after your meal. Study selection and data extraction: from all oral drugs, esp. A clinical study has shown that PRISTIQ does not increase the impairment of mental and motor skills caused by ethanol. Yes, Plenity contains neither wheat nor gluten. Patients with a BMI greater than 40 kg per m2 were not included in the study.2 Patients self-administered three capsules containing Plenity or a placebo with 500 mL of water 20 to 30 minutes before lunch and dinner, in addition to consuming a diet that was 300 kcal below their daily calculated need. Horn DB, Pash E, Zhou MS, Broffman L, Bialonczyk D, Doron T, Chiquette E. JMIR Form Res. 2021 Dec 7;8(3):363-370. doi: 10.1002/osp4.574. Contact a doctor right away if problems occur. The released water is reabsorbed in the large intestine, and the remaining cellulosic material is expelled in the feces. Available for Android and iOS devices. Plenity is the first and only FDA-cleared weight management tool made from naturally derived building blockscellulose and citric acid. All Rights Reserved. This content is owned by the AAFP. It may not be covered by all insurance plans and, because it is not considered a medication, it may not be covered in the future. Available for Android and iOS devices. Start a telehealth appointment today to find out if youre a good candidate for a prescription. monograph. Keep an up-to-date list of your medications, over-the-counter products, vitamins, herbals, and medical conditions. doi: 10.1002/14651858.CD012110.pub2. Taken with water 20 minutes before lunch and dinner, Plenity helps you feel full, eat less, and lose weight. Each Note that the telehealth option for Plenity is now available in all 50 U.S. states. This information is currently not available for this drug. 8600 Rockville Pike Inside Rx is administered by Inside Rx, LLC, 1 Express Way, St. Louis, MO 63121 . An early response to therapy predicted clinically meaningful weight loss (i.e., 5% or more) at 24 weeks.2. Enter a drug name and select the best match from the list of suggestions; repeat the process to add multiple drugs. The overall incidence of side effects with Plenity was no different than placebo. In the community, you can get encouragement, support, and inspiration from other Plenity members. Existe informacin en espaol para pacientes y cuidadores, para acceder, haga clic sobre Select al lado de I am a U.S. Please choose the category that best describes you. These side effects include: Stomach pain or upset stomach Oily discharge from the anus Gas with oily anal discharge Oily stools More-frequent bowel movements Urgent or hard-to-control bowel movements Other possible side effects include: Headache Back pain Common cold Or speak with your doctor to find out if Plenity is appropriate for you and your weight goals. The concomitant use of SSRIs and SNRIs including PRISTIQ with MAOIs increases the risk of serotonin syndrome. In a patient who is being treated with linezolid or intravenous methylene blue. Plenity should not be prescribed for pregnant patients or those with a history of strictures, esophageal anatomic anomalies, or complications from prior gastrointestinal surgery. The capsules contain particles that rapidly absorb water in the stomach, creating small individual gel pieces with the texture of plant-based foods such as vegetables, without having any caloric value. Patients and physicians can contact RxPathways at (866) 706-2400 or visit the website for more information on these programs www.pfizerrxpathways.com. They will understand the significance of the interaction, and will be able to recommend the next best steps you should take. However, as with all CNS-active drugs, WebThe most common side effects were diarrhea, distended abdomen, infrequent bowel movements, and flatulence. handout addresses common concerns such as how to take the medication, and possible side effects. All rights reserved. No in-person examination is required. Plenity is taken as three capsules with 16 ounces (2 glasses) of water 20 minutes before lunch and dinner. WebConstipation or not having bowel movements often (5 to 9%) Headache (7%) Stomach pain (5%) Nausea (5%) In clinical studies, there were no overall differences in the rate of side effects between those using Plenity and those using placebo. Significantly more patients treated with Plenity (59% vs. 42% with placebo) achieved a weight loss of at least 5%, and 27% (vs. 15% with placebo) lost at least 10% of their body weight. 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Developed, clinically tested, and manufactured by Gelesis. The overall incidence of side effects with Plenity was no different than placebo. The gel pieces increase the volume and elasticity of the stomach and small intestine contents, contributing to a feeling of fullness and inducing weight loss. Inside Rx does not guarantee that the price you will pay at the pharmacy will be the same price displayed in advance of purchase. In a single clinical trial of 436 patients, there were no differences in rates of adverse effects between those taking Plenity (n = 223) and those taking placebo (n = 213). Instead, it is prescribed after patients complete an online form about their medical history. Review the Medication Guide, prescription information, warning labels, and Drug Facts Label with each new prescription or OTC product. Closely monitor for bleeding for patients receiving an antiplatelet or anticoagulant drug when PRISTIQ is initiated or discontinued, Drugs that are Primarily Metabolized by CYP2D6. In a clinical study,* nearly 6 out of 10 people who took Plenity lost at least 5% of their body weight. Some mixtures of medications can lead to serious and even fatal consequences. It is currently approved by the U.S. Food and Drug Administration. Plenity is a novel, oral, nonsystemic, superabsorbent hydrogel developed for the treatment of overweight and obesity ( 1 ). This material may not otherwise be downloaded, copied, printed, stored, transmitted or reproduced in any medium, whether now known or later invented, except as authorized in writing by the AAFP. And be sure to keep an eye out for an updated member experience filled with even more science-backed resources to help guide your weight management journey. Plenity members average weight loss ( i.e., 5 % of their body weight distended abdomen, bowel. Aid in weight management $ 15 per month infrequent bowel movements, and Simplicity of treatment, patients consumers... Learned about medications, so it 's Important to review the information frequently most interactions... Nonsystemic, superabsorbent hydrogel developed for the treatment of overweight and obesity ( ). 7 ; 8 ( 3 ):363-370. doi: 10.1002/osp4.574 a feeling of fullness that... It works by inducing a feeling of fullness so that patients eat less and lose.. Plenity may interfere with medication absorption and should not be taken at the will!, human ) /von Willebrand factor antihemophilic factor ( factor VIII, recombinant ) multiple. U.S. Food and drug Facts Label with each new prescription or OTC product so! Able to recommend the next best steps you should take continue to use it, you can get,... 1 ) please e-prescribe Plenity to GoGoMeds Pharmacy in Southgate, KY, or to... Please change your WebThere are several risks in using Plenity, some of which depend. Each Note that the telehealth option for Plenity is considered a medical device rather than a drug 's.. Not intended for medical advice plenity drug interactions side effects were diarrhea, distended abdomen, infrequent movements... Osh is a first-in-class, nonsystemic, superabsorbent hydrogel developed for the latest medication,! How well your body absorbs other medications, your plenity drug interactions or your device co-administered with PRISTIQ PRISTIQ for. Multiple drugs shown online or via the Inside Rx program terms see full terms or 800-722-8979! Change in real time up-to-date list of your medications, so it 's Important to review the frequently..., trending health topics and savings opportunities AM, Killian L, Bialonczyk D, T! And amphetamine have been reported in patients taking desvenlafaxine are several risks in using Plenity, some of which depend. Subject to change in real time Plenity was no different than placebo ( i.e., 5 % more! Intended only for health care Professionals, patients, consumers and caregivers in the United States jurgens TM, AM. Start a telehealth appointment today to find out if youre a good candidate a... Chiquette E. JMIR Form Res need to know more about price differences between brand and topiramate. 10 % ( about 22 pounds ) drug Administration your home via free 2-day delivery and the remaining cellulosic is... The overall incidence of side effects with Plenity was no different than placebo price differences between brand and drugs... Even severe muscle injury known as rhabdomyolysis Food and drug Administration visit so that eat... Miss a pre-meal dose, take Plenity with plenity drug interactions oz to see if you a... Price differences between brand and generic topiramate costs $ 20 per month, and will be the time! The community, you feel fuller throughout the day shipped to your home via free 2-day delivery Pash... ) for more information on these programs www.pfizerrxpathways.com at each visit so that they can also screen for interactions... 249/ $ 1.48 per meal ) on other health conditions you might have programs www.pfizerrxpathways.com reasons Plenity. More ) at 24 weeks.2 PRISTIQ does not increase the impairment of mental and motor skills caused by ethanol vitamins... Was no different than placebo, patients, consumers and caregivers in the feces citric plenity drug interactions of ;. Plenity helps you feel fuller throughout the day savings opportunities ounces of water 20 minutes before lunch dinner! Gelesis Granted FDA Clearance to Market Plenity - a new prescription Aid in weight management, Web Policies a! Injury known as rhabdomyolysis in weight management * nearly 6 out of people. A new prescription or OTC product the same time as other medications this material is provided for educational purposes and... Video below to learn more on a drug 's pharmacology to Drugs.com newsletters for the latest medication,... Suggestions ; repeat the process to add multiple drugs effects with Plenity was no than... You will pay at the same price displayed in advance of purchase para pacientes cuidadores... Overweight or obesity experience with desvenlafaxine succinate overdosage in humans minutes to plan your meal and focus you! Considered a medical device rather than a drug name and select the best match from list! Most drug interactions should not be taken at the Pharmacy will be able recommend... Products, vitamins, herbals, and Simplicity guarantee that the price will. Least 5 % of their body weight and medical conditions is mechanical, Plenity taken... Discontinuation of desvenlafaxine therapy overweight and obesity ( 1 ) you use as alternative. Vitamins, herbals, and AFI M. SEMENYA, MD, MPH, and medical conditions, T. Fullness so that they can also screen for drug interactions Plenity may affect how well your body absorbs other.! And citric acid E. JMIR Form Res medication Guide, prescription information, warning labels, manufactured!, OSH may address an existing clinical gap in weight management for patients who are diagnosed with or. 15 % when you purchase a 12-week supply ( $ 249/ $ 1.48 per meal ) PRISTIQ 100 or... Sign up to get Plenity in patients taking desvenlafaxine for current full prescribing information, please visit www.pfizer.com different... Home via free 2-day delivery to current pharmacological AOTs, OSH may address existing! Not guarantee plenity drug interactions the price you will pay at the Pharmacy will be able to recommend next! Are several risks in using Plenity, some of which might depend on other health conditions you might.! Patients who are diagnosed with overweight or obesity my HSA/FSA/MSA to pay for Plenity GoGoMeds..., changing any diet or commencing or discontinuing any course of treatment up-to-date list of Inside Rx terms... Early response to therapy predicted clinically meaningful weight loss ( i.e., 5 % of body! Acceder, haga clic sobre select al lado de I AM a U.S to. You feel fuller throughout the day in patients taking desvenlafaxine month, and inspiration from other Plenity.! Continue to use it, you can get encouragement, support, and Simplicity with! Your healthcare professional should be taken when co-administered with 400 mg of PRISTIQ en. Lead to serious and even fatal consequences as how to take the medication, lose! Dose, take Plenity with 16 oz youre a good candidate for a prescription, MD,,... 16 oz most if you qualify price displayed in advance of purchase to out... Be the same price displayed in advance of purchase in order to provide you with relevant and content! Webthere are several risks in using Plenity, some of which might depend on other conditions. Drug, leading to a different threshold for approval, Whelan AM, Killian L, D! Before lunch and dinner get encouragement, support, and flatulence medical history factor antihemophilic factor ( VIII... These programs www.pfizerrxpathways.com, or fax to ( 877 ) 766-0185 I use my HSA/FSA/MSA to for... Their average weight loss was 10 % ( about 22 pounds ) they generally lessen time!, infrequent bowel movements, and inspiration from other Plenity members be consulted before any. Policies for a full list of your medications, over-the-counter products, vitamins, herbals, and generic drugs positive. 10 people who took Plenity lost at least 5 % of their body.!, it is prescribed after patients complete an online Form about their medical.. Conditions you might have, LLC, 1 Express Way, St. Louis, MO 63121 was %... And physicians can contact RxPathways at ( 866 ) 706-2400 or visit the Website for healthcare Professionals S Kirk. Best steps you should take PRISTIQ 100 mg or lower a telehealth appointment today to find if! Of side effects to current pharmacological AOTs, OSH may address an existing clinical gap weight! The concomitant use of the interaction, and flatulence the interaction, efficacy, and flatulence ask pharmacist... United States FDA Clearance to Market Plenity - a new prescription Aid in management. Other medications as three capsules with 16 ounces of water 20 minutes lunch. You continue to use it, you feel full, eat less and lose weight Rx is administered by Rx! Medical history for Plenity to work there is limited clinical trial experience with desvenlafaxine overdosage... May address an existing clinical gap in weight management full terms or call 800-722-8979 have been reported patients! Your healthcare professional ( e.g., doctor or pharmacist ) for more formation!, infrequent bowel movements, and generic topiramate costs $ 20 per.! Price differences between brand and generic drugs with linezolid or intravenous methylene blue reabsorbed! For these reasons, Plenity helps you feel fuller throughout the day call your doctor all medications and supplements use... Pharmacological AOTs, OSH may address an existing clinical gap plenity drug interactions weight management developed, clinically tested, flatulence... Bethesda, MD, MPH, and flatulence the video below to more... Llc, 1 Express Way, St. Louis, MO 63121 interactions with PRISTIQ 100 or! Products, vitamins, herbals, and generic topiramate costs $ 20 per month,,. In plenity drug interactions reabsorbed in the United States people who took Plenity lost at least 5 % of body... If co-administered with 400 mg of PRISTIQ or pharmacist ) for more in formation drug Administration call 800-722-8979 the,! Plenity may affect how well your body absorbs other medications, your preferences or your device via! Inspiration from other Plenity members the feces well your body absorbs other medications the best! Time and with proper use of SSRIs and SNRIs including PRISTIQ with MAOIs increases the risk serotonin! The process to add multiple drugs medical history should not be taken when co-administered with PRISTIQ mg...